Synthesis of (2-oxoindolin-3-ylidene)methyl acetates involving a C-H functionalization process.
نویسندگان
چکیده
A novel palladium-catalyzed oxidative C-H functionalization protocol for the synthesis of (2-oxoindolin-3-ylidene)methyl acetates has been developed. In the presence of Pd(OAc)2 and PhI(OAc)2, a variety of N-arylpropiolamides underwent the C-H functionalization reaction with acids to afford the corresponding (E)-(2-oxoindolin-3-ylidene)methyl acetates selectively in moderate to excellent yields.
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ورودعنوان ژورنال:
- Organic letters
دوره 10 9 شماره
صفحات -
تاریخ انتشار 2008